Wolff Competition 2025


UConn Chemists Developing Safer, All-Natural Contrast Dye for Medical Imaging

UConn Today – In the United States alone, more than 130 million MRIs and CT scans were performed in 2023. And while those medical images are very valuable tools in identifying, or ruling out, serious health problems, they are not without risk.

While the majority of patients experience no adverse effects, the contrast dyes used in the process can cause allergic reactions, and can trigger kidney damage in those with pre-existing kidney disease. The concern is greatest among people requiring multiple scans.

Pragati Rout, a doctoral candidate, and her mentor, chemistry professor Greg Sotzing, have found a plant-based alternative that is safe, effective, and free of allergic reaction. They’ve created a company, called 404 Inc., to market the medical innovation, as well as other consumer products.

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Startup ‘SeaSol’ Seeks to Convert Seaweed into Compostable Food Packaging, Replacing Plastic

UConn Today – When you visit your favorite sandwich, donut, or pizza shop next year, UConn Ph.D. candidate Yidan Zhang hopes you’ll be leaving with more than just good food. She wants you to also get a healthier food wrapper to carry it home.

Zhang is CEO of a startup called SeaSol Technologies, Inc. (DBA SeaSol), which is converting seaweed into a functional coating that makes food packaging compostable and high performance. The SeaSol team has developed a low-cost process that pares down the seaweed conversion process from 14 steps to one.

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New Startup’s Mission: Safer Deliveries for Moms and Babies

UConn Today – For many expectant parents, the countdown to the arrival of a new family member is filled with anticipation. They need to select a name, paint a nursery, stock up on diapers, and prepare for sleepless nights ahead.

Everyone hopes for a smooth and easy delivery, and no one champions that more than Dr. Andrea Shields. Shields is a professor in the Department of Obstetrics and Gynecology at UConn Health and the program director for the Maternal-Fetal Medicine Fellowship at the School of Medicine. She is working hard to decrease the risks that come with pregnancy and childbirth.

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Nutritional Startup Provides Healthy Meals to Keep Vulnerable People Out of the Hospital

UConn Today – Imagine the stress of just being discharged from the hospital–still feeling weak, vulnerable, and shaken by a serious diagnosis—only to be told that you now have to completely overhaul your diet.

That is a daunting task for many, but fortunately food expert Vanessa Sena and two colleagues from UConn Health have a solution.

They’ve started a business called MLC Nutrition, which provides delicious, healthy, chef-prepared meals for recently hospitalized patients, with the goal of optimizing their health and preventing rehospitalization.

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Wolff Finalist Startup ‘Orbit Crates’ Offers Subscription Toy Rentals for Kids

UConn Today – After a busy day at work, the last thing mother-of-three Kim Conti wanted to do was spend time sorting and organizing construction trucks, pretend-play toys, puzzle pieces—and those dreadful games that come with dozens of small parts. To help reduce household clutter and save toys from ending up in landfills, Conti has created Orbit Crates, a subscription toy-rental company.

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